Clinical Intelligence

Find What Changed. Explain Why It Matters.™

ARVELLIS helps care teams recognize clinically meaningful change, focus attention where it is warranted, and understand the reasoning behind each signal.

From baseline to a prioritized signalA patient's measurements vary around their own baseline. One change departs from it, is detected and prioritized, and is explained for clinical review.
Detect the change from an individual's baseline. Prioritize what warrants review. Explain why it matters.

More measurements do not automatically create better decisions.

Remote monitoring, patient engagement, wearables, call centers, and care management programs can collect important information. Yet teams still need a reliable way to identify meaningful change from baseline, determine what deserves attention, and explain why the change matters.

Patient Engagement System

A fuller clinical support model

The Patient Engagement System combines patient engagement, nursing support, escalation workflows, and physician-derived clinical intelligence. It is designed for organizations that need a broader operating model rather than an intelligence component alone.

Physician Intelligence Engine

A modular intelligence layer for the systems you already use

The Physician Intelligence Engine was developed within the Patient Engagement System and can also be deployed independently. PIE applies deterministic, physician-derived rules to changes from an individual's baseline and produces an explainable signal for human review.

When action is warranted, PIE can present multiple physician-approved options with the rationale for each. The treating clinician retains responsibility for selecting the appropriate course of action.

Detect, prioritize, explain

How PIE works

  1. Step 1

    Detect

    Recognize clinically meaningful change from the individual's baseline rather than treating every variation as equally important.

  2. Step 2

    Prioritize

    Distinguish signals that warrant attention so teams can focus limited clinical capacity where it matters.

  3. Step 3

    Explain

    Show why the signal matters and provide transparent, physician-derived reasoning that supports human review.

Modular integration

Use what already works. Add the intelligence that is missing.

PIE is designed to complement existing RPM or RTM platforms, care management programs, telehealth operations, wearables, call centers, and patient engagement systems. Organizations do not need to replace the infrastructure that already serves them.

Works alongside
  • RPM and RTM platforms
  • Care management programs
  • Telehealth operations
  • Wearables
  • Call centers
  • Patient engagement systems

PES and PIE, side by side

Capabilities of the Patient Engagement System and the Physician Intelligence Engine
CapabilityPESPIE
Best fitOrganizations needing a fuller operating modelOrganizations with infrastructure that need an intelligence layer
Patient engagementIncludedProvided by the host organization or partner
Nursing supportIncludedProvided by the host organization or partner
Escalation workflowIncludedIntegrates into existing workflow
Physician-derived intelligenceIncludedCore capability
DeploymentService modelModular integration
Human oversight

Intelligence that supports clinical judgment

ARVELLIS does not replace the treating clinician. PIE organizes and explains relevant information so qualified professionals can make informed decisions within their roles, workflows, and standards of care.
Initial pilot focus

Start with a defined population and measurable workflow

An initial pilot may focus on adults age 65 and older with one or two selected chronic conditions, such as congestive heart failure, chronic obstructive pulmonary disease, diabetes, or hypertension. Final population, measures, integration approach, and evaluation criteria should be agreed with the participating organization.

Common questions about PES and PIE